Boston Collaborative Drug Surveillance Program

By: Jeff | August 10, 2016

Authors: Meier CR, Derby LE, Jick SS, Jick H.
Published in: Arch Intern Med 2000;160:349-353
Abstract 1:

DID: 1
Authors: Meier CR, Derby LE, Jick SS, Jick H.
Title: Arch Intern Med 2000;160:349-353
Reference: Angiotensin-Converting Enzyme Inhibitors, Calcium Channel Blockers, and Breast Cancer
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Abstract:
Background: The use of angiotensin-converting enzyme (ACE) inhibitors has been linked to a decreased risk of developing cancer, and longer-term use of calcium channel blockers (CCBs) has been associated with an increased risk of developing cancer in general and breast cancer in particular. Methods: Using data from the General Practice Research Database, we conducted a large case-control analysis. Previous exposure to ACE inhibitors, C...

By: Jeff | August 10, 2016

Authors: Schlienger RG, Bircher AJ, Meier CR.
Published in: Dermatology 2000;200:223-231
Abstract 2:

DID: 2
Authors: Schlienger RG, Bircher AJ, Meier CR.
Title: Dermatology 2000;200:223-231
Reference: Minocycline-Induced Lupus
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Abstract:
Background: Minocycline has increasingly been associated with different adverse auto-immune reactions including drug-induced lupus. Objective: To identify the scope of minocycline-induced lupus and to characterize its typical features. Methods: Comprehensive Medline and Embase search of the English and non-English literature for case reports of minocycline-induced lupus. Results: We included 57 cases of minocycline-induced lupus (mean age ± SD at onset: 21.6 ± 8.6 years, median time of exposure: 19 mo...

Category: Publications 2000 

Tags: Dermatology 

By: Jeff | August 10, 2016

Author: Jick H. Published in: JAMA 2000;283:1738-1740

Category: Publications 2000 

Tags: JAMA 

By: Jeff | August 10, 2016

Authors: Gasse C, Derby LE, Vasilakis C, Jick H.
Published in: Br Med J 2000;320:1251
Abstract 4:

DID: 4
Authors: Gasse C, Derby LE, Vasilakis C, Jick H.
Title: Br Med J 2000;320:1251
Reference: Risk of suicide among users of calcium channel blockers
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Abstract:
We aimed to further investigate the possible association between use of calcium channel blockers and risk of suicide among people with hypertension based on information derived from the General Practice Research Database. We identified 153,458 patients with hypertension who had received a prescription for an antihypertensive drug between January 1991 and August 1998. Of these, we identified 38 subjects who committed suicide and matched them to 140 controls who were currently be...

Category: Publications 2000 

Tags: Brit Med J 

By: Jeff | August 10, 2016

Authors: Derby LE, Maier WC.
Published in: J Allergy Clin Immunol 2000;105:912-916
Abstract 5:

DID: 5
Authors: Derby LE, Maier WC.
Title: J Allergy Clin Immunol 2000;105:912-916
Reference: Risk of cataract among users of intranasal corticosteroids
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Abstract:
Background: Oral corticosteroid users are at increased risk of cataract, but the risk among intranasal corticosteroid users is unknown. Objective: Our purpose was to describe the risk of cataract among users of intranasal steroids. Methods: A retrospective observational cohort study of cataract incidence was conducted among users of oral and intranasal steroids identified from the United Kingdom-based General Practice Research Database with a nested case-control analysis to contro...

By: Jeff | August 10, 2016

Authors: Myers MW, Vasilakis C, Kaufman MR, Jick H.
Published in: Br J Clin Pharmacol 2000;49:604-608
Abstract 6:

DID: 6
Authors: Myers MW, Vasilakis C, Kaufman MR, Jick H.
Title: Br J Clin Pharmacol 2000;49:604-608
Reference: Antihypertensive drugs and the risk of idiopathic aplastic anemia
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Abstract:
Aims: This large population-based study evaluated the risk of idiopathic aplastic anemia in users of calcium channel blockers compared with that of other antihypertensive drugs. Methods: The study was based on information derived from the General Practice Research Database. We conducted a follow-up study with a nested case-control analysis of 322,448 subjects who received antihypertensive drugs. Cases were people who had a first-time di...

By: Jeff | August 10, 2016

Author: Meier CR.
Published in: J Infect Dis 2000;181(Suppl 3):S558-S562
Abstract 7:

 

DID: 7
Authors: Meier CR.
Title: J Infect Dis 2000;181(Suppl 3):S558-S562
Reference: Antibiotics in the prevention and treatment of coronary heart disease
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Abstract:
Seroepidemiology, pathology, and animal studies provide evidence for a possible association between Chlamydia pneumoniae infections and atherosclerosis, coronary heart disease, and myocardial infarction. If this association exists, then exposure to certain antibiotics may positively affect the clinical course after an acute ischemic cardiac event (secondary prevention) and affect the risk of developing a first-time myocardial infarction (primary prevention). Preliminary evidence from cli...

Category: Publications 2000 

Tags: J Infect Dis 

By: Jeff | August 10, 2016

Authors: Meier CR, Napalkov PN, Wegmüller Y, Jefferson T, Jick H.
Published in: Eur J Clin Microbiol Infect Dis 2000;19:834-842
Abstract 8:

DID: 8
Authors: Meier CR, Napalkov PN, Wegmüller Y, Jefferson T, Jick H.
Title: Eur J Clin Microbiol Infect Dis 2000;19:834-842
Reference: Population-based study on incidence, risk factors, clinical complications and drug utilization associated with influenza in the United Kingdom
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Abstract:
This large population-based study using the UK-based General Practice Research Database was conducted to quantify influenza-related physician visits, clinical complications of and risk factors for influenza, and related drug use in all age groups from 1991 to 1996. A total of 141,293 subjects who had one or mo...

By: Jeff | August 10, 2016

Authors: Gasse C, Derby L, Vasilakis-Scaramozza C, Jick H.
Published in: Pharmacotherapy 2000;20:629-634
Abstract 9:

DID: 9
Authors: Gasse C, Derby L, Vasilakis-Scaramozza C, Jick H.
Title: Pharmacotherapy 2000;20:629-634
Reference: Incidence of first-time idiopathic seizures in users of tramadol
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Abstract:
Study objective: To assess the risk of idiopathic incident seizures among patients who ever took tramadol. Design: Nested case-control design. Setting: General Practice Research Database from November 1996-August 1998. Patients: 11,383 patients. Intervention: Comparison of risks of idiopathic incident seizures during exposed and unexposed times among patients who had ever taken tramadol and other analgesics with 90-day follow-up. M...

By: Jeff | August 10, 2016

Authors: DeAbajo FJ, Jick H, Derby L, Jick S, Schmitz S.
Published in: Br J Clin Pharmacol 2000;50:43-47
Abstract 10:

DID: 10
Authors: DeAbajo FJ, Jick H, Derby L, Jick S, Schmitz S.
Title: Br J Clin Pharmacol 2000;50:43-47
Reference: Intracranial hemorrhage and use of selective serotonin reuptake inhibitors
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Abstract:
Aims: In the past few years an increasing number of bleeding disorders have been reported in association with the use of selective serotonin reuptake inhibitors (SSRIs), including serious cases of intracranial hemorrhage, raising concerns about the safety of this class of drugs. The present study was performed to test the hypothesis of an increased risk of intracranial hemorrhage associated with the use of SSRIs. Method...

By: Jeff | August 10, 2016

Authors: Meier CR, Schlienger RG, Kraenzlin ME, Schlegel B, Jick H.
Published in: JAMA 2000;283:3205-3210

Category: Publications 2000 

Tags: JAMA 

By: Jeff | August 10, 2016

Author: Jick SS.
Published in: Pharmacotherapy 2000;20:741-744
Abstract 12:

DID: 12
Authors: Jick SS.
Title: Pharmacotherapy 2000;20:741-744
Reference: The risk of gastrointestinal bleed, myocardial infarction, and newly diagnosed hypertension in users of meloxicam, diclofenac, naproxen, and piroxicam
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Abstract:
Study objective: To obtain formally quantified data on the relation of meloxicam to newly diagnosed gastrointestinal problems, myocardial infarction, or treated hypertension. Design: Nested case-control study. Setting: United Kingdom-based General Practice Research Database. Patients: Patients who received prescriptions for meloxicam, diclofenac, naproxen, or piroxicam formed the study population. Cases were people who develop...

By: Jeff | August 10, 2016

Authors: Melero Montes MM, Jick H.
Published in: Epidemiology 2000;12:123-124
Abstract 13:

DID: 13
Authors: Melero Montes MM, Jick H.
Title: Epidemiology 2000;12:123-124
Reference: Hyperemesis gravidarum and the sex of the offspring
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Abstract:
Studies have suggested that offspring of women hospitalized for hyperemesis gravidarum have a different sex ratio than those of women without this diagnosis, but little is known of the potential association between fetal gender and variables such as severity of hyperemesis, gestational trimester, and maternal age. Our findings provide evidence that pregnant women with a diagnosis of hyperemesis gravidarum in the first trimester give birth to a higher proportion of female newborns than do all mot...

Category: Publications 2000 

Tags: Epidemiology 

By: Jeff | August 10, 2016

Authors: Kaye JA, Derby LE, Melero Montes MM, Quinn M, Jick H.
Published in: Br J Cancer 2000;83:1556-1558
Abstract 14:

DID: 14
Authors: Kaye JA, Derby LE, Melero Montes MM, Quinn M, Jick H.
Title: Br J Cancer 2000;83:1556-1558
Reference: The incidence of breast cancer in the General Practice Research Database compared with national cancer registration data
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Abstract:
Breast cancer incidence rates in the UK from 1990 to 1996 among women aged 35-69 estimated from the General Practice Research Database (GPRD) were closely similar to those reported by the Office for National Statistics from cancer registration data (ONS). The GPRD is a valuable and up-to-date resource for further study of the incidence of breast cancer in the UK as well ...

Category: Publications 2000 

Tags: Br J Cancer 

By: Jeff | August 10, 2016

Zornberg GL, Jick H.

Published in: Lancet 2000;356:1219-1222
Abstract 15:

DID: 15
Authors: Zornberg GL, Jick H.
Title: Lancet 2000;356:1219-1222
Reference: Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism
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Abstract:
Background: Antipsychotic drugs have been associated with an increased risk of adverse events such as venous thromboembolism. Our aim was to assess this risk in users of conventional antipsychotic drugs who had been diagnosed with first-time, idiopathic venous thromboembolism. Methods: From a baseline population of 29,952 recipients of conventional and atypical antipsychotic drugs aged younger than 60 years, we identified 42 individuals with idiopathic venous thromboembolism and 172 matched c...

Category: Publications 2000 

Tags: Lancet 

By: Jeff | August 10, 2016

Authors: Jick SS, Kremers HM, Vasilakis-Scaramozza C.
Published in: Arch Dermatol 2000;136;1231-1236
Abstract 16:

DID: 16
Authors: Jick SS, Kremers HM, Vasilakis-Scaramozza C.
Title: Arch Dermatol 2000;136;1231-1236
Reference: Isotretinoin Use and Risk of Depression, Psychotic Symptoms, Suicide, and Attempted Suicide
No direct link.

Abstract:
Objective: To further investigate the proposed association between isotretinoin therapy and the risk of depression, psychotic symptoms, suicide, and attempted suicide using a formal study design. Design: Large population-based cohort studies. Setting: The Canadian Saskatchewan Health Database and the United Kingdom General Practice Research Database. Patients: Data were analyzed for 7,195 isotretinoin users and...

Category: Publications 2000 

Tags: Arch Dermatol 

By: Jeff | August 10, 2016

Authors: Jick H, Kaye JA, Vasilakis-Scaramozza C, Jick SS.
Published in: Br Med J 2000;321:1190-1195
Abstract 17:

DID: 17
Authors: Jick H, Kaye JA, Vasilakis-Scaramozza C, Jick SS.
Title: Br Med J 2000;321:1190-1195
Reference: Risk of venous thromboembolism among users of third generation oral contraceptives compared with users of oral contraceptives with levonorgestrel before and after 1995
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Abstract:
Objective: To compare the risk of idiopathic venous thromboembolism among women taking third generation oral contraceptives (with gestodene or desogestrel) with that among women taking oral contraceptives with levonorgestrel. Design: Cohort and case-control analyses derived from the General Practice Research Database. Setting: UK genera...

Category: Publications 2000 

Tags: Brit Med J 

By: Jeff | August 10, 2016

Authors: Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA.
Published in: Lancet 2000;356:1627-1631
Abstract 18:

DID: 18
Authors: Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA.
Title: Lancet 2000;356:1627-1631
Reference: Statins and the risk of dementia
No direct link.

Abstract:
Background: Dementia affects an estimated 10% of the population older than 65 years. Because vascular and lipid-related mechanisms are thought to have a role in the pathogenesis of Alzheimer’s disease and vascular dementia, we did an epidemiological study of the potential effect of HMGCoA (3 hydroxy-3methylglutaryl-coenzyme A) reductase inhibitors (statins) and other lipid-lowering agents on dementia. Methods: We used a nested case-control design with information...

Category: Publications 2000 

Tags: Lancet 

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