Boston Collaborative Drug Surveillance Program

By: Jeff | August 11, 2016

Authors: Seshadri S, Zornberg GL, Derby LE, Myers MW, Jick H, Drachman DA.
Published in: Arch Neurol 2001;58:435-440
Abstract 19:

DID: 19
Authors: Seshadri S, Zornberg GL, Derby LE, Myers MW, Jick H, Drachman DA.
Title: Arch Neurol 2001;58:435-440
Reference: Postmenopausal estrogen replacement therapy and the risk of Alzheimer’s disease
No direct link.

Background: Previous studies have examined the relation between postmenopausal estrogen replacement therapy (ERT) and the risk of Alzheimer’s disease. The findings have been inconsistent, since some studies have been interpreted as showing a protective effect while others have reported no effect. Objective: To determine whether exposure to ERT is associated with a reduced risk of Alzheimer’s...

Category: Publications 2001 

Tags: Arch Neurol 

By: Jeff | August 11, 2016

Authors: Jick SS, Vasilakis-Scaramozza C, Maier WC.
Published in: Epidemiology 2001;12:229-234
Abstract 20:

DID: 20
Authors: Jick SS, Vasilakis-Scaramozza C, Maier WC.
Title: Epidemiology 2001;12:229-234
Reference: The risk of cataract among users of inhaled steroids
No direct link.

Prolonged exposure to inhaled corticosteroids among adults over 49 years old has been reported to increase cataract risk. Small-scale studies of inhaled steroid users suggest that no increased risk for children and young adults exists. To describe cataract risk among people with asthma who use inhaled corticosteroids relative to patients with asthma with no history of corticosteroid use, we conducted a retrospective observational cohort study of patients identi...

Category: Publications 2001 

Tags: Epidemiology 

By: Jeff | August 11, 2016

Authors: Kaye JA, Melero-Montes MM, Jick H.
Published in: Br Med J 2001;322:460-463
Abstract 21:

DID: 21
Authors: Kaye JA, Melero-Montes MM, Jick H.
Title: Br Med J 2001;322:460-463
Reference: Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners
No direct link.

Objective: To estimate changes in the risk of autism and assess the relation of autism to the mumps, measles and rubella (MMR) vaccine. Design: Time trend analysis of data from the UK General Practice Research Database. Setting: General practices in the United Kingdom. Subjects: Children aged 12 years or younger diagnosed with autism 1988-99, with further analysis of boys aged 2 to 5 years born 1988-93. Main Outcome Measures: Annual and a...

Category: Publications 2001 

Tags: Brit Med J 

By: Jeff | August 11, 2016

Authors: Schlienger RG, Haefeli WE, Jick H, Meier CR.
Published in: Arch Intern Med 2001;161:2021-2026
Abstract 23:

DID: 23
Authors: Schlienger RG, Haefeli WE, Jick H, Meier CR.
Title: Arch Intern Med 2001;161:2021-2026
Reference: Risk of cataract in patients treated with statins
No direct link.

Background: Studies in dogs showed that some hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) are associated with cataract when administered in excessive doses. Clinical safety data of statins regarding cataract development in humans have been of limited value so far. Objective: To determine whether long-term use of statins is associated with an increased risk of cataract. Methods: We conducted a case-control analysis using data from...

By: Jeff | August 11, 2016

Authors: Jick H, Vasilakis-Scaramozza C, Jick SS.
Published in: Br J Clin Pharmacol 2001;52:451-453
Abstract 24:

DID: 24
Authors: Jick H, Vasilakis-Scaramozza C, Jick SS.
Title: Br J Clin Pharmacol 2001;52:451-453
Reference: Live attenuated polio vaccine and the risk of intussusception
No direct link.

Aims: Since suspicion has been raised that administration of an oral live attenuated rotavirus vaccine may increase the risk of intussusception in young children, there has been concern about the possible effects of oral polio vaccine. The aim of the study was to evaluate the relationship between oral attenuated polio vaccine and intussusception in children below the age of one year. Methods: We conducted a nested case-control analysis based ...

By: Jeff | August 10, 2016

Authors: Vasilakis-Scaramozza C, Jick H.
Published in: Lancet 2001;358:1427-1429
Abstract 25:

DID: 25
Authors: Vasilakis-Scaramozza C, Jick H.
Title: Lancet 2001;358:1427-1429
Reference: Risk of venous thromboembolism with cyproterone or levonorgestrel contraceptives
No direct link.

Results of studies have shown that there is an excess risk of venous thromboembolism in users of oral contraceptives containing cyproterone compared with those containing levonorgestrel. We did a case-control study, in which we assessed the risk of idiopathic venous thromboembolism in women taking combined low-dose estrogen oral contraceptives containing cyproterone (n=24,401) or levonorgestrel (n=75,000). We compared the 26 women in this population who had idi...

Category: Publications 2001 

Tags: Lancet 

By: Jeff | August 10, 2016

Authors: Kaye JA, Myers MW, Jick H.
Published in: Epidemiology 2001;12:690-694
Abstract 26:

DID: 26
Authors: Kaye JA, Myers MW, Jick H.
Title: Epidemiology 2001;12:690-694
Reference: Acetaminophen and the risk of renal and bladder cancer in the General Practice Research Database
No direct link.

We conducted a nested, matched case-control study in the General Practice Research Database (GPRD) to assess whether acetaminophen use is associated with renal or bladder cancer. We matched 109 cases of renal cancer and 189 cases of bladder cancer with up to 4 controls each by age, sex, general practice, duration of drug history in the GPRD, and index date. We found that use of acetaminophen from 1 to 5 years before the index date was associated wit...

Category: Publications 2001 

Tags: Epidemiology 




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