Boston Collaborative Drug Surveillance Program

By: Jeff | August 11, 2016

Authors: Jick H, Kaye JA.
Published in: Pharmacotherapy 2003;23:1524-1530
Abstract:

DID: 47
Authors: Jick H, Kaye JA.
Title: Pharmacotherapy 2003;23:1524-1530
Reference: Epidemiology and possible causes of autism
No direct link.

Abstract:
Objectives: To review the recent literature on possible causes of the increase in frequency of diagnosed autism reported from three countries, and to compare the medical diagnoses and drug therapy from a new series of autistic boys and their mothers with that of comparable nonautistic boys and their mothers. Design: Case-control evaluation. Participants: Members of over 250 general practices in the United Kingdom. Measurements and main results: Frequency of exposure to drugs and presence of pre-existing clinical il...

By: Jeff | August 11, 2016

Authors: Kaye JA, Bradbury BD, Jick H.
Published in: Br J Clin Pharmacol 2003;56:569-575
Abstract 46:

DID: 46
Authors: Kaye JA, Bradbury BD, Jick H.
Title: Br J Clin Pharmacol 2003;56:569-575
Reference: Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991 to 2000: a population-based observational study
No direct link.

Abstract:
Aim: To estimate changes in the frequency of use of various antipsychotic drugs in the UK from 1991 to 2000 and to relate these changes to patients’ characteristics. Methods: We conducted a population-based observational study using data from general practices that contribute information to the General Practice Research Database (GPRD). The study population comprised men and women...

By: Jeff | August 11, 2016

Authors: Jick H, Kaye JA, Black C.
Published in: Epidemiology 2003;14:630-632
Abstract 45:

DID: 45
Authors: Jick H, Kaye JA, Black C.
Title: Epidemiology 2003;14:630-632
Reference: Changes in risk of autism in the U.K. for birth cohorts, 1990-1998
No direct link.

Abstract:
Recently, we reported on the risk of first-time diagnosed autism for boys aged 2-5 years in annual birth cohorts of children born in 1988-1993. The study was based on information available in the U.K. General Practice Research Database (GPRD). Risks rose progressively throughout this study period and were 3-4 times higher in the 1993 birth cohort compared with the 1988 cohort. To determine whether the risks have continued to rise beyond the 1993 cohort, we examined birth cohorts o...

Category: Publications 2003 

Tags: Epidemiology 

By: Jeff | August 11, 2016

Authors: Schlienger RG, Meier CR .
Published in: Drugs Aging 2003;20:321-336
Abstract 44:

DID: 44
Authors: Schlienger RG, Meier CR .
Title: Drugs Aging 2003;20:321-336
Reference: HMG-CoA reductase inhibitors in osteoporosis. Do they reduce the risk of fracture?
No direct link.

Abstract:
Osteoporosis affects a large number of people in industrialized countries. It has clinical and public health impacts, most importantly due to subsequent fractures. Osteoporotic fractures are one of the most common causes of disability and are associated with enormous healthcare expenditure. The majority of existing treatment options for osteoporosis only inhibit bone resorption and prevent excessive bone loss but are not capable of stimulating bone formation. However...

By: Jeff | August 11, 2016

Authors: Jick SS, Kaye JA, Vasilakis-Scaramozza C, García Rodríguez LA, Ruigómez A, Meier CR, Schlienger RG, Black C, Jick H . 
Published in: Pharmacotherapy 2003;23:686-689
Abstract 43:

DID: 43
Authors: Jick SS, Kaye JA, Vasilakis-Scaramozza C, García Rodríguez LA, Ruigómez A, Meier CR, Schlienger RG, Black C, Jick H .
Title: Pharmacotherapy 2003;23:686-689
Reference: Validity of the General Practice Research Database
No direct link.

Abstract:
The United Kingdom General Practice Research Database (GPRD) is an office-based, computer-generated, medical resource designed from its inception to be used for epidemiologic research. A distinct version of the GPRD is maintained by the Boston Collaborative Drug Surveillance Program and has been the source of...

By: Jeff | August 11, 2016

Authors: Kaye JA, Jick H.
Published in: Br Med J 2003;326:424-425
Abstract 42:

DID: 42
Authors: Kaye JA, Jick H.
Title: Br Med J 2003;326:424-425
Reference: Incidence of erectile dysfunction and characteristics of patients before and after the introduction of sildenafil in the United Kingdom: cross sectional study with comparison patients
No direct link.

Abstract:
Objective: To estimate the incidence of erectile dysfunction (ED) and evaluate clinical characteristics of men diagnosed with ED before and after the introduction of sildenafil. Design: Follow-up and case-control analyses in the General Practice Research Database. Setting: UK general practices during the period, January 1990 to December 2000. Participants: Men aged 40-79. Main outcome meas...

Category: Publications 2003 

Tags: Brit Med J 

By: Jeff | August 11, 2016

Authors: Yang CC, Jick SS, Testa MA.
Published in: Br J Clin Pharmacol 2003;56:84-91
Abstract 41:

DID: 41
Authors: Yang CC, Jick SS, Testa MA.
Title: Br J Clin Pharmacol 2003;56:84-91
Reference: Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics
No direct link.

Abstract:
Aims: To evaluate the effects of comorbidities and patient characteristics on treatment continuation among patients starting their first course of lipid-lowering drug (LLD) therapy. Methods: Within the UK General Practice Research Database (GPRD), we identified 22,408 patients who started LLD therapy due to coronary heart disease, hyperlipidemia, or other atherosclerotic diseases, and who receiv...

By: Jeff | August 11, 2016

Authors: Yang CC, Jick SS, Testa MA. 
Published in: Br J Clin Pharmacol 2003;55:288-298
Abstract:

DID: 40
Authors: Yang CC, Jick SS, Testa MA.
Title: Br J Clin Pharmacol 2003;55:288-298
Reference: Who receives lipid-lowering drugs: effects of comorbidities and patient characteristics on treatment initiation
No direct link.

Abstract:
Aims: Little is known about the effects of comorbidities and patients characteristics on treatment initiation of lipid-lowering drugs (LLDs), which can be helpful in the evaluation of the risks and benefits of LLDs. Methods: Baseline characteristics among subjects who received their first ever-recorded LLD prescription in general practice between January 1, 1990 and December 31, 1997, and hyperlipidemic patients without ...

By: Jeff | August 11, 2016

Authors: Yang CC, Jick SS, Jick H. 
Published in: Arch Intern Med 2003;163:1926-1932
Abstract 39:

DID: 39
Authors: Yang CC, Jick SS, Jick H.
Title: Arch Intern Med 2003;163:1926-1932
Reference: Lipid-lowering drugs and the risk of depression and suicidal behavior
No direct link.

Abstract:
Background: A possible association between lipid-lowering drug therapy and psychological well-being remains an issue of debate. To provide more information, we performed a nested case-control study to evaluate the effect of lipid-lowering drugs on depression and suicidal behavior. Methods: Within the United Kingdom General Practice Research Database, we identified all cases with newly treated depression needing a referral or hospitalization and all cases with first...

Category: Publications 2003 

Tags: Arch Int Med 

By: Jeff | August 11, 2016

Authors: Wood SL, Jick H, Sauve R. 
Published in: Diabetic Medicine 2003;20:703-707
Abstract : 38

DID: 38
Authors: Wood SL, Jick H, Sauve R.
Title: Diabetic Medicine 2003;20:703-707
Reference: The risk of stillbirth in pregnancies before and after the onset of diabetes
No direct link.

Abstract:
Aims: There is significant controversy as to whether or not stillbirth is increased in pregnancies prior to the onset of diabetes. An observed increase may be indicative of risks associated with untreated gestational diabetes. It is generally accepted that the risk of stillbirth in pregnancies that occur after the onset of diabetes has been diminished by modern obstetric care. However, the degree of residual risk is not well quantified. This study sought to e...

By: Jeff | August 11, 2016

Authors: Black C, Kaye JA, Jick H.
Published in: Br J Clin Pharmacol 2003;55:107-111
Abstract 37:

DID: 37
Authors: Black C, Kaye JA, Jick H.
Title: Br J Clin Pharmacol 2003;55:107-111
Reference: MMR vaccine and idiopathic thrombocytopenic purpura
No direct link.

Abstract:
Aims: To estimate the relationship between idiopathic thrombocytopenic purpura (ITP) and the measles, mumps and rubella (MMR) vaccination in children; calculating the relative risk estimate for ITP within 6 weeks after MMR vaccination and the attributable risk of ITP within 6 weeks after MMR vaccination. Methods: Using the General Practice Research Database we identified children with a first-time diagnosis of ITP from a base population of children aged less than 6 years between Ja...

Tags

JAMA

Pharmacotherapy

J Am Geriatrics

J Clin Psychopharmacol

Teratology

Arch Int Med

Post Marketing Surveillance

Pharmacoepidemiology & Drug Safety

Epidemiology

Lancet

Med J Australia

Obstet Gynecol

Brit Med J

The Medical Journal of Australia

Pharmacoepidemiology & Drug Safety

Brit J General Practice

Epilepsia

Clinical Orthopaedics

Brit J Psychiatry

The Pediatric Infectious Disease Journal

Brit J Clin Pharmacology

Thorax

J Rheumatology

N Engl J Med

Cardiovascular Drugs and Therapy

J Am Acad Dermatol

JACC

Biomed & Pharmacother

Contraception

Diabetes Care

Biomedicine & Pharmacotherapy

Arch Dermatol

Br J Cancer

Eur J Clin Microbiol Infect Dis

J Infect Dis

J Allergy Clin Immunol

Dermatology

Arch Intern Med 2000

Br J Clin Pharmacol

Arch Intern Med

Arch Neurol

J Hepatology

J Clin Psychiatry

Diabetic Medicine

Drugs and aging

injury Prev

drug Safety

Breast Cancer Research & Treatment

Neurology

British Journal of Caner

Pediatrics

Am J Cardiology

Thromb Haemost

Cancer Causes & Control

Arch Neurology

Brain

Cancer

Amer J Epidemiol

Pharmacoepidemiology & Drug Safety

Arthritis Care & Research

J Neurol

Headache

Cephalalgia

Brit J. Dermatol

Brit J Dermatol

Paediatric and Perinatal Epidemiolog

J Investig Dermatol

Eur J Neurol

Climacteric

Br J Haematol

Ann Rheum Dis

J Roy Soc Med

Parkinsonism Relat Disord

Chest

BMC Neurology

Ann Intern Med

Eur J Epidemiol

Vaccine

COPD

J Clin Endocrinol Metab

Br J Haematol doi

Pragmatic and Observational Research

DOI

Eur J Neurol DOI

Br Med J

Epidemiol Res Intl

Menopause

Gynecologic Oncology

Digestive and Liver Disease

Cancer Epidemiol Biomarkers Prev

Am J Gastroenterol

Evidence-Based Nursing

J Am Geriatr Soc

Respirology

Respiration

Br J Dermatol

Waugh N. Technology Assessment

Acta Orthopaedica

Lung Cancer

Pain Physician

J Intern Med

Cancer Epidemiol

Am J Epidemiol

Eur J Prev Cardiol

Alzheimer’s Dis

Travel Medicine and Infectious Disease

BMJ Open

J Invest Dermatol

Cancer Causes Control

J Invest Dermato

Ann Allergy Asthma Immunol

Drug Safety

Pädiatrie

Evid Based Nurs

Clinical and Experimental Allergy

J Clin Endocrinology & Metabolism

J Dev Behav Pediatr

Int J Clin Pract

Ann Rheumatol

Diabetes Obes Metab

Ann Epidemiol

Orthopedic Muscul Sys

Br J Cance

Cancer Epidemiology

Epidemiol Infect

Travel Med Infec Dis

J Natl Cancer Inst

An International Journal of Obstetrics and Gynaecology

Ann Hematol.

Ann Hematol

Intl J Cancer

Clin Epidemiol

CNS Drugs

Ann Med

BMC Cancer

J Clin Rheumatol

BJOG

J Crohns Colitis

J Neurooncol

Mod Rheumatol

J Diabetes Complications

Brain Behav Immunity

Neuro Oncol

Behavior

and Immunity

Osteoarthritis Cartilage

PLoS One

Clin Exp Allergy

Paediatr Perinat Epidemiol

Inflamm Bowel Dis

Pharmacoepidemiol Drug Saf

Diabet Med

BMJ