Authors: Currin L, Schmidt U, Treasure J, Jick H.
Published in: Brit J Psychiatry 2005;186:132=135.
Abstract 65:

DID: 65
Authors: Currin L, Schmidt U, Treasure J, Jick H.
Title: Brit J Psychiatry 2005;186:132=135.
Reference: Time trends in eating disorder incidence
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Abstract:
Background During the years 1988-1993 the primary care incidence of anorexia nervosa in the UK remained stable, but the incidence of bulimia nervosa increased threefold. Aims To determine whether the incidence of anorexia nervosa remained stable, and that of bulimia nervosa continued to increase, in the years 1994-2000. Method The General Practice Research Database was screened for new cases of anorexia and bulimia nervosa between 1994 and 2000. Annual incidence ...

Authors: Bradbury BD, Lash TL, Kaye JA, Jick SS.
Published in: Cancer 2005;103:1114-21.
Abstract 66:

DID: 66
Authors: Bradbury BD, Lash TL, Kaye JA, Jick SS.
Title: Cancer 2005;103:1114-21.
Reference: Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newly-diagnosed angina
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Abstract:
Background It is known that tamoxifen therapy favorably affects blood cholesterol levels and other cardiovascular disease risk factors; however, to our knowledge, few studies to date have reported a lower risk of heart disease for breast carcinoma patients who are treated with tamoxifen. METHODS A nested, matched, case-control study design was used with data from the General Practice Research Database to examine w...

Authors: Kaye JA, Jick H.
Published in: Epidemiology 2005;16:688-690.
Abstract 67:

DID: 67
Authors: Kaye JA, Jick H.
Title: Epidemiology 2005;16:688-690.
Reference: Antibiotic use and the risk of breast cancer
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Abstract:
Background: Two recent studies found a positive association between antibiotic use and the risk of breast cancer. Methods: Using information from the U.K. General Practice Research Database, we identified 1268 cases of incident breast cancer (40- to 79-year-old women diagnosed in 1987 to 2002 who had at least 6 years of history recorded in the General Practice Research Database) and 6291 female controls matched to the cases on age, general practice, and duration of history recorded in the General Practice Research Dat...

Authors: Black C, Kaye JA, Jick H.
Published in: Obstet Gynecol 2005;106:151-5.
Abstract 68:

DID: 68
Authors: Black C, Kaye JA, Jick H.
Title: Obstet Gynecol 2005;106:151-5.
Reference: Cesarean delivery in the United Kingdom: Time trends in the General Practice Research Database
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Abstract:
Objective: To estimate recent temporal trends in delivery by cesarean during the past decade and the proportion of vaginal deliveries after prior caesarean in the United Kingdom. Methods: We conducted a cohort study using information from the General Practice Research Database. We identified all women with 1 or more deliveries between January 1990 and December 1999 and determined the method(s) of delivery. We estimated the proportion of women with v...

Authors: Russmann S, Kaye JA, Jick SS, Jick H.
Published in: Brit J Clin Pharmacol 2005;60:76-82.
Abstract 69:

DID: 69
Authors: Russmann S, Kaye JA, Jick SS, Jick H.
Title: Brit J Clin Pharmacol 2005;60:76-82.
Reference: Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database
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Abstract:
AIMS: To provide additional quantification of the risk of flucloxacillin-related liver disease and to describe time trends in flucloxacillin prescribing in the UK. METHODS: This was a cohort study using data from the UK General Practice Research Database. We identified patients with a first-time prescription for flucloxacilli...

Authors: Hernan MA, Jick SS, Logroscino G, Olek MJ, Ascherio A, Jick H.
Published in: Brain 2005;128:1461-5.
Abstract 70:

DID: 70
Authors: Hernan MA, Jick SS, Logroscino G, Olek MJ, Ascherio A, Jick H.
Title: Brain 2005;128:1461-5.
Reference: Cigarette smoking and the progression of multiple sclerosis
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Abstract:
An increased risk of multiple sclerosis among smokers has been found in several prospective epidemiological studies. The association between smoking and progression of multiple sclerosis has not been examined. We identified patients who had a first multiple sclerosis diagnosis recorded in the General Practice Research Database (GPRD) between January 1993 and December 2000. Their diagnosis and date of first symptoms were confir...

Authors: Alonso A, Jick SS, Olek MJ, Ascherio A, Jick H, Hernan MA.
Published in: Arch Neurology 2005;62;1362-5.
Abstract 71:

DID: 71
Authors: Alonso A, Jick SS, Olek MJ, Ascherio A, Jick H, Hernan MA.
Title: Arch Neurology 2005;62;1362-5.
Reference: Recent use of oral contraceptives and the risk of multiple sclerosis
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Abstract:
Background: Exogenous estrogens affect the onset and clinical course of experimental allergic encephalomyelitis. Oral contraceptives, a frequent source of exogenous estrogens in humans, could have a role in the development of multiple sclerosis (MS). Objective: To examine whether recent oral contraceptive use and pregnancy history are associated with the risk of MS. DESIGN AND SETTING: A case-control study nes...

Authors: Bradbury BD, Wilk JB, Kaye JA.
Published in: Cancer Causes & Control 2005;16:637-641.
Abstract 72:

DID: 72
Authors: Bradbury BD, Wilk JB, Kaye JA.
Title: Cancer Causes & Control 2005;16:637-641.
Reference: Obesity and the risk of prostate cancer (United States)
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Abstract:
The role of obesity in prostate cancer etiology remains controversial. A recent report suggested that obese men younger than age 60 may have a lower risk of developing prostate cancer than men the same age who are not obese. The current study used a nested, matched case-control study design and data collected in the General Practice Research Database between January 1991 and December 2001 to assess the association between body mass index (BMI) and th...

Authors: Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
Published in: Pharmacotherapy 2005;25:503-510.
Abstract 73:

DID: 73
Authors: Fischer LM, Schlienger RG, Matter CM, Jick H, Meier CR.
Title: Pharmacotherapy 2005;25:503-510.
Reference: Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction
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Abstract:
Subjects. A total of 8688 case patients, aged 89 years or younger, with a first-time acute myocardial infarction and 33,923 control subjects matched on age, sex, calendar time, and general practice attended. Intervention. The United Kingdom General Practice Research Database was searched for potential cases of first-time acute myocardial infarction between January 1995 and April 2001. C...

Authors: Gasse C, Hollowell J, Meier CR, Haefeli WE.
Published in: Thromb Haemost 2005;94:537-43.
Abstract 74:

DID: 74
Authors: Gasse C, Hollowell J, Meier CR, Haefeli WE.
Title: Thromb Haemost 2005;94:537-43.
Reference: Drug interaction and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin
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Abstract:
Although drug interactions with warfarin are an important cause of excessive anticoagulation, their impact on the risk of serious bleeding is unknown. We therefore performed a cohort study and a nested case-control analysis to determine the risk of serious bleeding in 4152 patients (aged 40-84 years) with nonvalvular atrial fibrillation (AF) taking long-term warf...