Boston Collaborative Drug Surveillance Program

By: Jeff | October 24, 2016

Authors: Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
Published in: Headache 2008;48:606-10.
Abstract 92:

DID: 92
Authors: Becker C, Brobert GP, Almqvist PM, Johansson S, Jick SS, Meier CR.
Title: Headache 2008;48:606-10.
Reference: The risk of newly diagnosed asthma in migraineurs with or without previous triptan prescriptions
No direct link.

Abstract:
Background: Previous observational studies reported an increased prevalence of asthma in migraine patients. Whether triptans affect the asthma risk has not yet been explored in an epidemiological study. Objective.—To estimate the risk of newly diagnosed asthma in patients with a general practitioner-diagnosed migraine in the UK between 1994 and 2001. Methods.—A population-based ...

Category: Publications 2008 

Tags: Headache 

By: Jeff | October 24, 2016

Authors: Jick SS, Li L. 
Published in: Pharmacotherapy 2008;28(2):144-150.
Abstract 93:

DID: 93
Authors: Jick SS, Li L.
Title: Pharmacotherapy 2008;28(2):144-150.
Reference: Antidepressant drugs in relation to venous thromboembolism
No direct link.

Abstract:
Study Objective. To evaluate the risk of idiopathic venous thromboembolism associated with antidepressant use and to further assess the risk by class of antidepressant and by individual antidepressant drug. Design. Nested case-control study. Data Source. United Kingdom General Practice Research Database. Subjects. Seven hundred eighty-two case patients with a confirmed diagnosis of venous thromboembolism who were taking an antidepressant drug and 3085 matched control subjects. Measurements and M...

By: Jeff | October 24, 2016

Authors: Brauchli YB, Jick SS, Curtin F, Meier CR.
Published in: J Am Acad Dermatol 2008;58:421-9.
Abstract 94:

DID: 94
Authors: Brauchli YB, Jick SS, Curtin F, Meier CR.
Title: J Am Acad Dermatol 2008;58:421-9.
Reference: Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: a population-based case-control study
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Abstract:
Background: Small clinical trials suggest that thiazolidinediones may exert a beneficial effect on skin lesions of patients with psoriasis. Little is known about other classes of antidiabetic drugs and the psoriasis risk. Objective: We sought to study the association between use of thiazolidinediones, sulfonylureas, biguanides, or acarbose and the risk of developing a first-time d...

By: Jeff | October 24, 2016

Authors: Meier C, Kraenzlin ME, Bodmer M, Jick SS, Jick H, Meier CR.  
Published in: Arch Int Med 2008;168:820-5.
Abstract 95:

DID: 95
Authors: Meier C, Kraenzlin ME, Bodmer M, Jick SS, Jick H, Meier CR.
Title: Arch Int Med 2008;168:820-5.
Reference: Use of thiazolidinediones and fracture risk
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Abstract:
Background: Thiazolidinediones may adversely affect the skeleton owing to decreased bone formation and accelerated bone loss. METHODS: This study examines the association between the use of thiazolidinediones or other oral antidiabetic drugs and the risk of fracture. This nested case-control analysis uses the UK General Practice Research Database, including case patients with fracture aged 30 to 89 years with an incident fracture diag...

Category: Publications 2008 

Tags: Arch Int Med 

By: Jeff | October 24, 2016

Authors: Kaye JA, Jick H.  
Published in: Pharmacotherapy 2008;28:951-9.
Abstract 96:

DID: 96
Authors: Kaye JA, Jick H.
Title: Pharmacotherapy 2008;28:951-9.
Reference: Proton pump inhibitors and hip fractures in patients without major risk factors
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Abstract:
Study Objective. To estimate the relative risk of hip fracture associated with proton pump inhibitor (PPI) use in a population without major risk factors. Design. A two-phase, matched, nested case-control study. Data Source. United Kingdom General Practice Research Database (GPRD). Patients. Phase 1 identified 4414 case patients (aged 50–79 yrs) with an incident hip fracture between 1995 and 2005 who had at least 2 years of recorded history in the GPRD; each case was matched by a...

By: Jeff | October 24, 2016

Authors: Kaye JA, Li L.  
Published in: Brit J Dermatol 2008;159:895-902.
Abstract 97:

DID: 97
Authors: Kaye JA, Li L.
Title: Brit J Dermatol 2008;159:895-902.
Reference: Incidence of risk factors for myocardial infarction and other vascular diseases in patients with psoriasis
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Abstract:
Background: Recent cross-sectional studies reported a higher prevalence of diabetes and other risk factors for cardiovascular disease in patients with psoriasis than in the general population. ObjectiveS: To estimate the cumulative incidences of risk factors for myocardial infarction and other vascular diseases after a first recorded diagnosis of psoriasis and the hazard ratio (HR) for these conditions in patients with psoriasis compared with the gene...

By: Jeff | October 24, 2016

Authors: Brauchli YB, Jick SS, Curtin F, Meier CR.  
Published in: Brit J. Dermatol 2008;158:1299-1307.
Abstract: 98

DID: 98
Authors: Brit J.
Title: Dermatol 2008;158:1299-1307.
Reference: Association between beta-blockers, other antihypertensive drugs and psoriasis: population-based case-control study
No direct link.

Abstract:
Background: Several case reports have associated use of beta-blockers with an increased risk of psoriasis or psoriasiform drug eruptions. ObjectiveS: To study the association between use of beta-blockers and other antihypertensive drugs and the risk of developing a first-time diagnosis of psoriasis. METHODS: We conducted a case-control analysis on the U.K.-based General Practice Research Database. We identified cases with an ...

By: Jeff | October 24, 2016

Authors: Becker C, Jick SS, Meier CR. 
Published in: Neurology 2008;70:1438-44.
Abstract 99:

DID: 99
Authors: Becker C, Jick SS, Meier CR.
Title: Neurology 2008;70:1438-44.
Reference: Use of antihypertensives and the risk of Parkinson disease
No direct link.

Abstract:
Background: Recent studies related angiotensin converting enzyme (ACE) inhibitors and calcium channel blockers to possible neuroprotective effects. Little is known about neuroprotection of angiotensin II (AT II) antagonists or beta-blockers. Objective: To explore the association between antihypertensive drug use and the risk of developing a first-time diagnosis of Parkinson disease (PD). Methods: This was a case-control analysis within the UK-based General Practice Research Database. C...

Category: Publications 2008 

Tags: Neurology 

By: Jeff | October 24, 2016

Authors: Becker C, Jick SS, Meier CR.
Published in: Drug Safety 2008;31:399-407.
Abstract 100:


DID: 100
Authors: Becker C, Jick SS, Meier CR.
Title: Drug Safety 2008;31:399-407.
Reference: Use of statins and the risk of Parkinson’s disease: a retrospective case-control study in the UK
No direct link.


Abstract:
Background: Case reports have related the use of HMG-CoA reductase inhibitors (‘statins’) to Parkinson’s disease (PD). Paradoxically, however, statins may have potentially beneficial effects on neurodegenerative diseases due to their anti-inflammatory properties. Objective: To explore the risk of the development of PD in association with untreated hyperlipidaemia and with hyperlipidaemia treated with lipid-lowering drugs in the UK primary care...

Category: Publications 2008 

Tags: drug Safety 

By: Jeff | October 24, 2016

Authors: Becker C, Jick SS, Meier CR.
Published in: Drug Safety 2008;31:399-407.
Abstract 100:


DID: 100
Authors: Becker C, Jick SS, Meier CR.
Title: Drug Safety 2008;31:399-407.
Reference: Use of statins and the risk of Parkinson’s disease: a retrospective case-control study in the UK
No direct link.


Abstract:
Background: Case reports have related the use of HMG-CoA reductase inhibitors (‘statins’) to Parkinson’s disease (PD). Paradoxically, however, statins may have potentially beneficial effects on neurodegenerative diseases due to their anti-inflammatory properties. Objective: To explore the risk of the development of PD in association with untreated hyperlipidaemia and with hyperlipidaemia treated with lipid-lowering drugs in the UK primary care...

Category: Publications 2008 

Tags: drug Safety 

By: Jeff | October 21, 2016

Authors: Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
Published in: Diabetes Care 2008;31:1808-12.
Abstract 101:

DID: 101
Authors: Becker C, Brobert GP, Johansson S, Jick SS, Meier CR.
Title: Diabetes Care 2008;31:1808-12.
Reference: Diabetes in patients with idiopathic Parksinson’s disease
No direct link.

Abstract:
Objective: Previous observational studies reported inconsistent results on the association between diabetes and Parkinson’s disease, and data on the risk of developing incident diabetes in relation to Parkinson’s disease are scarce. We aimed at comparing the diabetes prevalence between patients with or without Parkinson’s disease and at exploring the risk of developing incident diabetes associated with Parkinson’s disease. RESEA...

Category: Publications 2008 

Tags: Diabetes Care 

By: Jeff | October 21, 2016

Authors: Becker C, Brobert G, Almqvist P, Johansson S, Jick SS, Meier CR.
Published in: Cephalalgia 2008;28:57-64.
Abstract 102:

DID: 102
Authors: Becker C, Brobert G, Almqvist P, Johansson S, Jick SS, Meier CR.
Title: Cephalalgia 2008;28:57-64.
Reference: Migraine incidence, comorbidity and health resource utilization in the United Kingdom
No direct link.

Abstract:
Population-based data on migraine incidence and comorbidity are scarce. We therefore aimed to quantify incidence rates and comorbidity of diagnosed migraine and health resource utilization (HRU) in migraineurs in the UK primary care setting. We conducted a follow-up study with a nested case-control analysis on the General Practice Research Database. The study encompassed 51,688 patients ...

Category: Publications 2008 

Tags: Cephalalgia 

By: Jeff | October 21, 2016

Authors: Bodmer M, Meier C, Krahenbuhl S, Jick SS, Meier CR.
Published in: Diabetes Care 2008;31:2086-91.
Abstract 103:

DID: 103
Authors: Bodmer M, Meier C, Krahenbuhl S, Jick SS, Meier CR.
Title: Diabetes Care 2008;31:2086-91.
Reference: Metformin, sulfonylureas or other antidiabetic drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis
No direct link.

Abstract:
Objective: Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim of this study was to compare the risk of lactic acidosis and hypoglycemia among patients with type 2 diabetes using oral antidiabetes drugs. RESEARCH DESIGN AND METHODS: This study is a nested case-control analysis using the U.K.-...

Category: Publications 2008 

Tags: Diabetes Care 

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