Boston Collaborative Drug Surveillance Program

By: Jeff | August 11, 2016

Authors: Yang CC, Jick SS, Testa MA.
Published in: Br J Clin Pharmacol 2003;56:84-91
Abstract 41:

DID: 41
Authors: Yang CC, Jick SS, Testa MA.
Title: Br J Clin Pharmacol 2003;56:84-91
Reference: Discontinuation and switching of therapy after initiation of lipid-lowering drugs: the effects of comorbidities and patient characteristics
No direct link.

Abstract:
Aims: To evaluate the effects of comorbidities and patient characteristics on treatment continuation among patients starting their first course of lipid-lowering drug (LLD) therapy. Methods: Within the UK General Practice Research Database (GPRD), we identified 22,408 patients who started LLD therapy due to coronary heart disease, hyperlipidemia, or other atherosclerotic diseases, and who receiv...

By: Jeff | August 11, 2016

Authors: Black C, Kaye JA, Jick H.
Published in: Br J Clin Pharmacol 2003;55:107-111
Abstract 37:

DID: 37
Authors: Black C, Kaye JA, Jick H.
Title: Br J Clin Pharmacol 2003;55:107-111
Reference: MMR vaccine and idiopathic thrombocytopenic purpura
No direct link.

Abstract:
Aims: To estimate the relationship between idiopathic thrombocytopenic purpura (ITP) and the measles, mumps and rubella (MMR) vaccination in children; calculating the relative risk estimate for ITP within 6 weeks after MMR vaccination and the attributable risk of ITP within 6 weeks after MMR vaccination. Methods: Using the General Practice Research Database we identified children with a first-time diagnosis of ITP from a base population of children aged less than 6 years between Ja...

By: Jeff | August 11, 2016

Authors: Yang C, Jick SS, Jick H.
Published in: Br J Clin Pharmacol 2002;53:101-105
Abstract 27:

DID: 27
Authors: Yang C, Jick SS, Jick H.
Title: Br J Clin Pharmacol 2002;53:101-105
Reference: Statins and the risk of idiopathic venous thromboembolism
No direct link.

Abstract:
Aims: To evaluate the association between current statin use and the risk of idiopathic venous thromboembolism (VTE). Methods: A population-based retrospective follow-up with a nested case-control analysis using the General Practice Research Database. Results: There were 72 cases of idiopathic VTE. Using normolipidemic nonuse as the reference group, the adjusted relative risks for idiopathic VTE for current/recent statin use, past statin use, past other lipid-lowering drug use,...

By: Jeff | August 11, 2016

Authors: Schlienger RG, Jick H, Meier CR.
Published in: Br J Clin Pharmacol 2002;54:327-332
Abstract 33:

DID: 33
Authors: Schlienger RG, Jick H, Meier CR.
Title: Br J Clin Pharmacol 2002;54:327-332
Reference: Use of nonsteroidal anti-inflammatory drugs and the risk of first-time acute myocardial infarction
No direct link.

Abstract:
Aims: Aspirin decreases the risk of clinical manifestations of atherothrombosis. This effect is mainly due to inhibition of platelet aggregation and potentially due to anti-inflammatory properties of aspirin. To evaluate whether use of non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) may also be associated with a decreased risk of first-time acute myocardial infarction (AMI), we performed a population-based case...

By: Jeff | August 11, 2016

Authors: Jick H, Vasilakis-Scaramozza C, Jick SS.
Published in: Br J Clin Pharmacol 2001;52:451-453
Abstract 24:

DID: 24
Authors: Jick H, Vasilakis-Scaramozza C, Jick SS.
Title: Br J Clin Pharmacol 2001;52:451-453
Reference: Live attenuated polio vaccine and the risk of intussusception
No direct link.

Abstract:
Aims: Since suspicion has been raised that administration of an oral live attenuated rotavirus vaccine may increase the risk of intussusception in young children, there has been concern about the possible effects of oral polio vaccine. The aim of the study was to evaluate the relationship between oral attenuated polio vaccine and intussusception in children below the age of one year. Methods: We conducted a nested case-control analysis based ...

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