Boston Collaborative Drug Surveillance Program

By: Jeff | October 24, 2016

Authors: Li L, Jick H, Jick SS.  
Published in: Brit J Clin Pharmacol 2009;68:269-70. 
Abstract 111:

DID: 111
Authors: Li L, Jick H, Jick SS.
Title: Brit J Clin Pharmacol 2009;68:269-70.
Reference: Updated study on the risk of cholestatic liver disease and flucloxacillin (letter).
No direct link.

Abstract:
112 Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database

By: Jeff | October 21, 2016

Authors: Jick SS, Kaye JA, Jick H.  
Published In: Brit J Clin Pharmacol 2007;64:662-7.
Abstract 85:

DID: 85
Authors: Jick SS, Kaye JA, Jick H.
Title: Brit J Clin Pharmacol 2007;64:662-7.
Reference: Diclofenac and acute myocardial infarction in patients with no major risk factors
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Abstract:
Aims To explore further a recent finding that long-term users of diclofenac are at increased risk of acute myocardial infarction (AMI) similar to users of rofecoxib and celecoxib. Methods Using the General Practice Research Database, we conducted three separate nested case–control studies of three nonsteroidal anti-inflammatory drugs (NSAIDs) where use started after 1 January 1993 — diclofenac, ibuprofen and naproxen. Cases of AMI were identified b...

By: Jeff | October 20, 2016

Authors: Russmann S, Kaye JA, Jick SS, Jick H.
Published in: Brit J Clin Pharmacol 2005;60:76-82.
Abstract 69:

DID: 69
Authors: Russmann S, Kaye JA, Jick SS, Jick H.
Title: Brit J Clin Pharmacol 2005;60:76-82.
Reference: Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database
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Abstract:
AIMS: To provide additional quantification of the risk of flucloxacillin-related liver disease and to describe time trends in flucloxacillin prescribing in the UK. METHODS: This was a cohort study using data from the UK General Practice Research Database. We identified patients with a first-time prescription for flucloxacilli...

By: Jeff | October 20, 2016

Authors: Jick SS, Bradbury BD.
Published in: Brit J Clin Pharmacol 2004;58:303-309.
Abstract 55:

DID: 55
Authors: Jick SS, Bradbury BD.
Title: Brit J Clin Pharmacol 2004;58:303-309.
Reference: Statins and newly diagnosed diabetes
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Abstract:
Aims In order to evaluate a hypothesized protective effect of the use of HMG Co-A reductase inhibitors (statins) on the development of Type 2 diabetes, we conducted a nested case–control study based on data from the UK-based General Practice Research Database (GPRD). Methods We identified a population of adults 30–79 years of age between 1 January 1991 and 31 March 2002, who were being treated with a statin or who were diagnosed with hyperlipidaemia but were not being treated with a lipid-lowering ...

By: Jeff | October 20, 2016

Authors: Bradbury BD, Jick H.
Published in: Brit J Clin Pharmacol 2004;58:209-211.
Abstract 57:

DID: 57
Authors: Bradbury BD, Jick H.
Title: Brit J Clin Pharmacol 2004;58:209-211.
Reference: In vitro fertilization and childhood retinoblastoma
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Abstract:
Aims To estimate the frequency of childhood retinoblastoma among children conceived by in vitro fertilization (IVF). Methods Using the United Kingdom-based General Practice Research Database (GPRD), we identified all live births, cases of retinoblastoma and IVF procedures occurring between January 1989 and December 2001. Results We identified 0 cases of retinoblastoma among 176 children conceived by IVF (Risk = 0/176, one-sided 97.5% CI 0, 0.02) and 24 cases of retinoblastoma diagnosed...

By: Jeff | August 11, 2016

Authors: Kaye JA, Bradbury BD, Jick H.
Published in: Br J Clin Pharmacol 2003;56:569-575
Abstract 46:

DID: 46
Authors: Kaye JA, Bradbury BD, Jick H.
Title: Br J Clin Pharmacol 2003;56:569-575
Reference: Changes in antipsychotic drug prescribing by general practitioners in the United Kingdom from 1991 to 2000: a population-based observational study
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Abstract:
Aim: To estimate changes in the frequency of use of various antipsychotic drugs in the UK from 1991 to 2000 and to relate these changes to patients’ characteristics. Methods: We conducted a population-based observational study using data from general practices that contribute information to the General Practice Research Database (GPRD). The study population comprised men and women...

By: Jeff | August 11, 2016

Authors: Yang CC, Jick SS, Testa MA. 
Published in: Br J Clin Pharmacol 2003;55:288-298
Abstract:

DID: 40
Authors: Yang CC, Jick SS, Testa MA.
Title: Br J Clin Pharmacol 2003;55:288-298
Reference: Who receives lipid-lowering drugs: effects of comorbidities and patient characteristics on treatment initiation
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Abstract:
Aims: Little is known about the effects of comorbidities and patients characteristics on treatment initiation of lipid-lowering drugs (LLDs), which can be helpful in the evaluation of the risks and benefits of LLDs. Methods: Baseline characteristics among subjects who received their first ever-recorded LLD prescription in general practice between January 1, 1990 and December 31, 1997, and hyperlipidemic patients without ...

By: Jeff | August 11, 2016

Authors: Black C, Kaye JA, Jick H.
Published in: Br J Clin Pharmacol 2002;53:637-640
Abstract 31:

DID: 31
Authors: Black C, Kaye JA, Jick H.
Title: Br J Clin Pharmacol 2002;53:637-640
Reference: Clinical risk factors for venous thromboembolus in users of the combined oral contraceptive pill
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Abstract:
Aims: To estimate the risk of venous thromboembolism among women prescribed the oral contraceptive pill who have acute clinical conditions such as lower limb fractures, compared with women with idiopathic venous thromboembolism. Methods: A nested case-control analysis using the General Practice Research Database, January 1993 to December 1999 was carried out. The participants were women aged 15-39 years, prescribed third generation oral ...

By: Jeff | August 10, 2016

Authors: Myers MW, Vasilakis C, Kaufman MR, Jick H.
Published in: Br J Clin Pharmacol 2000;49:604-608
Abstract 6:

DID: 6
Authors: Myers MW, Vasilakis C, Kaufman MR, Jick H.
Title: Br J Clin Pharmacol 2000;49:604-608
Reference: Antihypertensive drugs and the risk of idiopathic aplastic anemia
No direct link.

Abstract:
Aims: This large population-based study evaluated the risk of idiopathic aplastic anemia in users of calcium channel blockers compared with that of other antihypertensive drugs. Methods: The study was based on information derived from the General Practice Research Database. We conducted a follow-up study with a nested case-control analysis of 322,448 subjects who received antihypertensive drugs. Cases were people who had a first-time di...

By: Jeff | August 10, 2016

Authors: DeAbajo FJ, Jick H, Derby L, Jick S, Schmitz S.
Published in: Br J Clin Pharmacol 2000;50:43-47
Abstract 10:

DID: 10
Authors: DeAbajo FJ, Jick H, Derby L, Jick S, Schmitz S.
Title: Br J Clin Pharmacol 2000;50:43-47
Reference: Intracranial hemorrhage and use of selective serotonin reuptake inhibitors
No direct link.

Abstract:
Aims: In the past few years an increasing number of bleeding disorders have been reported in association with the use of selective serotonin reuptake inhibitors (SSRIs), including serious cases of intracranial hemorrhage, raising concerns about the safety of this class of drugs. The present study was performed to test the hypothesis of an increased risk of intracranial hemorrhage associated with the use of SSRIs. Method...

By: Jeff | August 10, 2016

Authors: Derby LE, Myers MW, Jick H.
Published in: Brit J Clin Pharmacol 1999;47:565-569.

By: Jeff | August 10, 2016

Authors: Myers MW, Jick H. Published in: Brit J Clin Pharmacol 1998;46:251-3.

By: Jeff | August 10, 2016

Authors: Meier CR, Jick H. Published in: Brit J Clin Pharmacol 1998;45:608-612.

By: Jeff | August 10, 2016

Authors: Jick SS, Vasilakis C, Martinez C, Jick H. 
Published in: Brit J Clin Pharmacol 1998;45:77-81.

By: Jeff | August 10, 2016

Authors: Meier CR, Jick H. Published in: Brit J Clin Pharmacol 1997;44:175-178.

By: Jeff | August 04, 2016

Authors: Myers, MW, Jick H. Published in: Brit J Clin Pharmacology 1997;43:446-448.

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