Boston Collaborative Drug Surveillance Program

By: Jeff | October 25, 2016

Imfeld P, Bodmer M, Schuerch M, Jick SS, Meier CR.
Neurology. 2013 Sep 3;81(10):910-19. doi: 10.1212/WNL.0b013e3182a35151. Epub 2013 Jul 31.

Category: Publications 2013 

Tags: Neurology 

By: Jeff | October 24, 2016

Authors: Becker C, Jick SS, Meier CR. 
Published in: Neurology 2008;70:1438-44.
Abstract 99:

DID: 99
Authors: Becker C, Jick SS, Meier CR.
Title: Neurology 2008;70:1438-44.
Reference: Use of antihypertensives and the risk of Parkinson disease
No direct link.

Background: Recent studies related angiotensin converting enzyme (ACE) inhibitors and calcium channel blockers to possible neuroprotective effects. Little is known about neuroprotection of angiotensin II (AT II) antagonists or beta-blockers. Objective: To explore the association between antihypertensive drug use and the risk of developing a first-time diagnosis of Parkinson disease (PD). Methods: This was a case-control analysis within the UK-based General Practice Research Database. C...

Category: Publications 2008 

Tags: Neurology 

By: Jeff | October 20, 2016

Authors: Alonso A, Jick S, Hernan MA.  
Published in: Neurology 2006;66:572-5.
Abstract 78:

DID: 78
Authors: Alonso A, Jick S, Hernan MA.
Title: Neurology 2006;66:572-5.
Reference: Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis
No direct link.

Background: It is unclear whether allergic diseases are associated with multiple sclerosis (MS), but histamine 1 receptor blockers, used in the treatment of allergic conditions, decreased the severity of experimental autoimmune encephalomyelitis (an animal model of MS). Objective: To assess the association of allergy history and use of histamine 1 receptor blockers with the risk of MS. METHODS: Using a case-control study nested in the United Kingdom-based General Practice ...

Category: Publications 2006 

Tags: Neurology 

By: Jeff | October 20, 2016

Authors: Hernan MA, Jick SS, Olek MJ, Jick H.
Published in: Neurology 2004;63:838-842.
Abstract 58:

DID: 58
Authors: Hernan MA, Jick SS, Olek MJ, Jick H.
Title: Neurology 2004;63:838-842.
Reference: Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study
No direct link.

Background: A potential link between the recombinant hepatitis B vaccine and an increased risk of multiple sclerosis (MS) has been evaluated in several studies, but some of them have substantial methodologic limitations. METHODS: The authors conducted a nested case-control study within the General Practice Research Database (GPRD) in the United Kingdom. The authors identified patients who had a first MS diagnosis recorded in the GPRD between ...

Category: Publications 2004 

Tags: Neurology 




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